Epilepsy, Sleep and Sleep Deprivation

Epilepsy and Sleep: Sleep Hygiene and Obstructive Sleep Apnea, Sleep Deprivation, Circadian Patterns and Epilepsy Surgery

The relationship between epilepsy and sleep is complex and dynamic. Sleep complaints and concomitant sleep disorders are common in people with epilepsy. Seizures and antiepileptic drugs can alter sleep architecture.There have been conflicting findings on the impact of sleep deprivation on seizures; however there is evidence to support the improved specificity of epilepsy diagnosis when a negati...

Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans

Sleep has been proposed to be a physiological adaptation to conserve energy, but little research has examined this proposed function of sleep in humans. We quantified effects of sleep, sleep deprivation and recovery sleep on whole-body total daily energy expenditure (EE) and on EE during the habitual day and nighttime. We also determined effects of sleep stage during baseline and recovery sleep...

Sleep deprivation, sleep apnea and cardiovascular diseases.

Sleep dramatically influences cardiovascular regulation. Changes in sleep duration or quality as seen in sleep disorders may prevent blood pressure to fall during sleep as expected in human physiology. This supports the increased prevalence of hypertension and drug-resistant hypertension in those with sleep loss. Other cardiovascular outcomes i.e. coronary lesions seem to be associated with sle...

Sleep deprivation

Sleep deprivation in the rat: III. Total sleep deprivation.

Ten rats were subjected to total sleep deprivation (TSD) by the disk apparatus. All TSD rats died or were sacrificed when death seemed imminent within 11-32 days. No anatomical cause of death was identified. All TSD rats showed a debilitated appearance, lesions on their tails and paws, and weight loss in spite of increased food intake. Their yoked control (TSC) rats remained healthy. Since dehy...